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ICDMO AI Services

AI Digital Library Construction Services

AI-Based High-Throughput Gene & Protein Interaction Screening Libraries

Build comprehensive digital 3D protein libraries for any species in 14 days — covering whole genomes, transcription factors, or custom gene sets. Zero reagent cost. Immediate availability for 100+ species.

Zero Experimental Cost
Confidence-Scored Results
Publication-Ready Figures
Wet-Lab Validation Available
24h Scientific Support

Service Overview

ICDMO's AI-powered digital library construction service simulates vast species' gene pools and builds comprehensive 3D protein structural libraries optimized for high-throughput interaction screening. Rather than constructing physical yeast or phage display libraries (which require months), our platform generates AI-predicted 3D protein models for every gene in your target species, creating a complete digital library ready for immediate large-scale screening. Libraries are validated against known interaction data and continuously updated with the latest genomic databases.

Technical Advantages

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Zero Experimental Cost
Fully automated AI service eliminates all reagent, cloning, and transformation expenses associated with traditional library construction.
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14 Days vs. 3–4 Months
Dramatically faster than traditional experimental library construction — receive your complete digital library in two weeks.
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Ready-to-Use for 100+ Species
Pre-built whole-genome libraries for major model organisms and crops available immediately. Custom species built on request.
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3D Structure + Core Interaction Analysis
Each library entry includes AI-generated 3D protein model, modeling confidence score, and core interaction site analysis.
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Seamlessly Integrated with Screening
Directly compatible with Library-to-Library Interaction Screening, AI-PPI, and Binding Site Prediction services.
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Optional Yeast Validation
One-on-one yeast validation services available to experimentally confirm key digital hits.

Available Digital Library Types

Transcription Factor (TF) Digital Libraries — 21 Plant Species

▸Soybean (Glycine max): 6,150 TFs
▸Wheat (Triticum aestivum): 3,606 TFs
▸Maize (Zea mays): 3,308 TFs
▸Arabidopsis (A. thaliana): 2,296 TFs
▸Rice, Cotton, Tobacco, Tomato, and 13 additional species
▸Custom TF libraries for any species — provide genome annotation

Whole Genome Digital Libraries — 50+ Species

▸Arabidopsis thaliana: 27,434 genes
▸Soybean (Glycine max): 55,799 genes
▸Rice (Oryza sativa): 43,649 genes
▸Homo sapiens: 23,391 genes
▸Mus musculus: 21,615 genes
▸Danio rerio (Zebrafish): 24,664 genes
▸E. coli: 4,363 genes | S. cerevisiae: 6,039 genes
▸Pathogens, parasites, and custom organisms available

Species-Specific & Custom Libraries

▸Banana (Musa acuminata) auxin/gibberellin-related: 3,528 genes
▸Pathway-specific libraries: hormone signaling, immune response, metabolic networks
▸Custom gene set libraries: provide amino acid or CDS sequences
▸Cross-species interaction libraries for virus–host or symbiosis studies

How Digital Libraries Are Used

1Library-to-Library Screening: Screen bait library A × prey library B for all pairwise interactions (millions of pairs)
2One-to-Many Screening: Screen a single protein of interest against an entire genome-wide library
3TF-Target Identification: Identify transcription factor binding partners across the proteome
4Virus–Host Interaction: Cross-species screening to map pathogen–host interaction networks
5Drug Target Discovery: Screen target protein against compound or peptide digital libraries

Service Timeline & Deliverables

Service ContentTurnaroundDeliverables
Sequence extraction / sorting from provided input1 working dayComplete Excel data sheet with all gene/protein IDs and annotations
Complete 3D structural modeling of all library members14 working days3D Modeling Scoring Table with model confidence scores; PDB files for all proteins; Core interaction site analysis
Custom species library (genome annotation required)14–21 working daysCustom digital library ready for immediate screening
Optional: downstream Library-to-Library ScreeningPer screening timelineInteraction network Excel, ranked pairs, visualization

Service Process

1
Online Consultation
2
Solution Matching
3
Service Contract
4
AI Computation
5
Project Report

Note: All services are for research use only and not intended for diagnostic or therapeutic purposes.

Get a Custom Quote

Our scientific team responds within 24 hours with a detailed technical proposal and pricing tailored to your research goals.

Contact Us Online Consultation

Standard Deliverables

✓Detailed analysis report (PDF)
✓Raw data files & processed outputs
✓High-resolution publication figures
✓Interaction scoring tables (Excel)
✓Project summary presentation

Related AI Services

Digital Library-to-Library ScreeningProtein Interaction & Binding Site PredictionDigital Protein/Nucleic Acid Interaction ModelMolecular Dynamics SimulationAI Multimodal Protein–Compound ScreeningCustom Libraries Construction
Why ICDMO AI?
19+ Years of Experience
Clients in 40+ Countries
Wet-Lab Validation Integrated
24h Response Guarantee